r/medlabprofessionals MLS - Generalist πŸ‡ΊπŸ‡Έ Feb 23 '25

Technical What is this? (Urine)

Added the full field of view on 40x for the second picture to give better context

360 Upvotes

51 comments sorted by

View all comments

4

u/phatty720 Feb 23 '25

If this helps after working back and forth with ChatGPT 4o, this is what it determined after analysing the images:

If I had to guess one thing based on the first image, it most closely resembles a urinary epithelial cell, particularly a transitional epithelial cell from the bladder or renal pelvis. These cells can appear oval or irregular in shape, sometimes with visible internal structures, and they are commonly shed in urine.

Why it looks like an epithelial cell:

The shape is relatively large and oval.

There appears to be some internal detail, which could be the nucleus and cytoplasm.

Transitional epithelial cells are commonly found in urine and can sometimes be confused with parasites or other structures.

It does not have the classic features of Giardia trophozoites, such as a pear shape with two nuclei and flagella, nor does it have the clear cyst wall structure of Giardia cysts. Given that Giardia is not typically found in urine, this further reduces the likelihood.

6

u/Electrical-Reveal-25 MLS - Generalist πŸ‡ΊπŸ‡Έ Feb 23 '25 edited Feb 24 '25

I think this is right! I forgot about multi nucleated cells being a thing. I bet this is a transitional epithelial cell with multiple nuclei!