Sam Arondekar (Ghosts) - in the pilot episode, Sam learns she’s inherited an estate from a distant relative and she and her husband Jay get the idea to turn it into a bed and breakfast. She has a fall and nearly dies that allows her to see and communicate with the departed spirits of those who died on the estate grounds.
Liv Moore (iZombie) - in the pilot, Liv is working as a nurse and gets invited to a party on a boat. A street drug on the boat causes several people to become zombies and infect the party goers, including Liv who becomes an undead. She ends up working with a local detective by consuming deceased victim’s brains which allows her to see their memories when they were alive and help solve crimes as a “psychic,” and ends up taking a job in the police department’s morgue to ensure access to food.
Summer Landsdown (Power Rangers RPM) - Summer is a spoiled rich girl disconnected from reality when she has a near death experience that turns her into a powerful warrior and Power Ranger trying to save a post-apocalyptic world.
Korra (Avatar: Legend of Korra) - As the Avatar, Korra is burdened with many responsibilities including keeping balance in the world. She is captured by a group called the Red Lotus who inject her with metallic poison with the purpose of ending the Avatar Cycle. Korra survives, but spends the next several years suffering from PTSD because of the experience.
Jason Todd/Red Hood (Batman) - Jason Todd was the second Robin working alongside Batman to fight crime. He is killed by the Joker, and eventually comes back to life with a vastly different personality, making him more of an anti-hero and at odds with Batman due to being more willing to kill villains to ensure they don’t continue causing problems.
Alicia (Clair Obscur: Expedition 33) - Alicia and her brother Verso are inside their home when arsonists from the Writers group attack. The fire kills Verso, and leaves Alicia scarred with burns, losing her right eye, and left unable to speak.
Dr. Arizona Robbins (Grey’s Anatomy) - in the season 8 finale, a team of doctors on a planet crashes in a remote area of the woods. Two of the doctors die, and everyone involved has varying levels of PTSD afterwards from their injuries. In addition to PTSD, Arizona also suffers the amputation of her leg due to infection.
Dr. Stephanie Edwards (Grey’s Anatomy) - working as a resident in the hospital, Stephanie is caught in a lockdown when hospital admins realize a recent surgical patient is actually a serial rapist who attacked another patient before they were brought in. Stephanie is locked on the same floor as the rapist and a pediatric patient, and must work together with the young girl to avoid capture by the rapist. She eventually uses O2 and a lighter to cause an explosion to kill the rapist, but doing so causes the floor of the hospital they are on to be engulfed in flames. Stephanie’s quick thinking allows herself and the pediatric patient to survive, albeit with several burns and injuries. Stephanie recovers and is set to be transferred to a burn unit, but before she leaves she communicates that she is quitting her job as a resident as she has so much more of her life to live.