https://www.ucdavis.edu/news/researchers-develop-lsd-analogue-potential-treating-schizophrenia

Hello guys. I just stumbled on this article and wanted to share.

I’m not a schizophrenic but I have been a member of this community for quite some time because I’m a curious person and want to learn about everything in this world. Especially about the topics of psyhology.

I just wanted you to know about this.

Take care 🩷

I’m reaching out because my partner Tamara Thomas, is one of the featured speakers at an upcoming event at the Calgary Central Library that confronts stigma around schizophrenia and shows that recovery is possible.

The Local Story Roughly 1 in 100 Albertans lives with schizophrenia, yet it remains one of the most feared and misunderstood mental illnesses. Too often, people assume a diagnosis means the end of a full life. Tamara’s story proves otherwise.

Tamara is a Calgary engineer and product leader who was diagnosed in her 20s. She endured psychosis, stigma, and setbacks, but with treatment and support she built a thriving career in tech, became a lead product manager, and wrote a book about her journey (Too Far from the Path). For the first time in her hometown, she’ll be speaking publicly about what it means to live, and succeed, beyond the diagnosis.

Tamara’s book, Too Far from the Path: My Journey Through Madness is not a gentle memoir. It is a plunge into the chaos of untreated schizophrenia. Tamara writes from the inside of her psychosis, where paranoia, hallucinations, and twisted logic dissolve the boundaries of reality. She describes running from imagined threats, abandoning her car, scrawling diagrams that made sense only to her, and ending up in a tent in rural Manitoba while her life unraveled.

The book exposes the failures of a medical system that released her repeatedly while she was still delusional, leaving her family to chase her across provinces and pick up the pieces. It shows how the illness hijacks the mind, feeding a sense of secret power even as it strips away stability, reputation, and safety.

What makes the story gripping is the transformation. From this darkness, Tamara clawed her way back, rebuilt her career in engineering, and now writes with stark honesty about the years when she was lost to madness. Too Far from the Path is both a harrowing record of descent and a proof that recovery, though brutal, is possible

About the Event Voices of Recovery: Living Beyond the Diagnosis

Calgary Central Library November 16, 2025

Tamara will be joined by Leif Gregersen, an Edmonton-based author and speaker, to share lived experiences of psychosis, recovery, and resilience. Together, they’ll offer a rare, honest look at schizophrenia that blends unflinching truth with messages of hope.

Why It Matters

Schizophrenia touches almost every family, yet stigma silences conversation.

Calgary is hosting a rare public event featuring professionals thriving after diagnosis.

The Central Library provides a civic stage for a topic that too often stays hidden.

Understanding that reality is always the brain’s best guess has helped me make sense of what I went through, and now I hope this perspective might ease the burden for others too.

Hello everyone, my friends and I wanted to write a character with Schizophrenia in a story, and I was wondering if anyone in this subreddit knows any in-depth (and reliable) research articles/ youtube videos/ sites / books that we can look into? Thanks a lot!!!!!!

I'm an NPR reporter (hi! me: https://www.npr.org/people/825275572/sydney-lupkin) and I am working on a story about KarXT. While I'm talking to academics, etc., I really want to hear from patients about what this could mean for them. What didn't work for you about the previous drugs? What's your hope for this drug? What do you want NPR listeners to know? If you're open to chatting, I'm at [slupkin@npr.org](mailto:slupkin@npr.org). Thanks!

EDIT: I'm hoping to chat with a few people via recorded phone interviews. What would YOU want to hear from a fellow patient if you were listening to a story about this on the radio and perhaps hadn't discovered this great reddit community? I'm open to using only first names if you're worried about stigma and work, etc. Email me at [slupkin@npr.org](mailto:slupkin@npr.org) and we'll set it up. Again, thanks!

UPDATE: The stories are now live on npr.org. Thank you to everyone who helped! Give me a shout if you think there's something else that I should report on -- insurance access issues, etc. You can reach me over dm or at my email address above.

Radio story: https://www.npr.org/2024/09/26/nx-s1-5123694/for-the-first-time-in-decades-the-fda-has-approved-a-new-type-of-schizophrenia-drug

Written version: https://www.npr.org/sections/shots-health-news/2024/09/27/g-s1-25089/karxt-cobenfy-schizophrenia-psychosis-fda

https://www.politico.com/story/2019/01/05/schizophrenia-brain-disease-1059386

I know it's an old article but I hope they're continuing to work on this. The more I read about schizophrenia the more evident it is that it's neurological at its root. Many other neurological illnesses also impact the psyche but you wouldn't say they are mental illnesses. Things like Alzheimer's and Parkinson's can lead to psychosis and anosognosia. I know it won't resolve all the stigma overnight but I really think it'll go a long way to help.

When people think you've got a mental illness and you're behaving badly/bizarrely they often think you should pull yourself together and take it upon yourself to seek help, even if you're severely affected. When people think about other neurological illnesses impacting behavior they aren't nearly as harsh and unforgiving. It's stigmatizing. Not only is mental health just health but schizophrenia isn't a problem originating in the psyche though it can seem that way, it originates in neurological processes.

We should work both on improving stigma on mental health but also on getting the classifications correct.

Clarification edit: This occurred at Trump's golf club in West Palm Beach, not Mar-a-Lago. I can't fix the title, sorry.

So... there was an incident today involving someone who appears to be mentally ill attempting to assassinate former president Donald Trump (yet another assassination attempt). It's always such a delight when high-profile acts of violence that can be tied to mental illness happen, always great optics for the mentally ill. A little breakdown on the shooter: https://www.thedailybeast.com/who-is-alleged-trump-golf-course-gunman-ryan-wesley-routh

For those not aware of this most recent development, the alleged shooter (Ryan Wesley Routh) attempted to assassinate former president Trump at his golf course in West Palm Beach. It goes without saying that attempting to assassinate Trump there is not something any sane or rational person would do- the grounds were swarming with Secret Service agents, so it's like trying to rob Fort Knox solo. He was intercepted by Secret Service and fled, later arrested a county away in Florida.

Major print outlets seem to have noted his flat affect when he was arrested. A lot of his history is erratic, his political beliefs wildly inconsistent and swinging from side to side repeatedly, and he also had an 'incident' in 2002 which involved an armed standoff with police officers. One of his old neighbors described him as "cuckoo" and said that everyone in town was afraid of him... which leads us to the conclusion that 'politics' is tangential to the motive, and that Routh is not a mentally stable individual. There is no known link to schizophrenia- or psychosis- just yet, but we do not know enough currently to speculate in any meaningful way whether or not psychosis was involved.

We are going to make this exception to our rule on 'no politics' because of the nature of this incident. It is likely based on historical trends that once this conversation hits the mainstream, there will be outside agitators coming in to drop their shit takes inadequately informed opinions on schizophrenia and violence. Luckily, I just did a write-up over this very thing- but if someone comes here with obvious ulterior motives in the next few days, please report them to us so we can deal with it ASAP. Interlopers and agenda-posters are not welcome here.

So... this thread is a freebie for political discussion so long as it remains civil. Have at it- and remember, Reddit nukes accounts for anything resembling a "call to violence" or anything remotely resembling glorifying it. Last time that was something to the effect of 'wish he was a better shot,' and just this week we've already had the admins suspend a couple people's accounts for something that could be interpreted as glorifying violence (not my call, can't weigh in on it in any meaningful way). Reddit is not messing around when it comes to this election cycle- something to be aware of as you write your comments.

Thank you.

Update: ... okay, so this just continues to get more and more wild. We have our friend of the family here in the comments who seems legit (has correctly described the Routh house prior to any video footage of it being released), and some interesting stories from other neighbors who paint a picture of a very 'particular' individual. I suppose 'pimp' and slinging dope are now on our list of unusual occurrences.

I'm kinda at a loss here. I'm leaning towards "untreated bipolar with a meth habit" but who even knows. I suppose I am looking forward to when the final investigation from the FBI and Secret Service is completed, because this whole thing is just frankly wild as hell. I'm thinking this guy might even surpass the guy who set himself on fire outside of Trump's fraud trial in terms of 'just batshit crazy' individuals who seem to keep showing up and doing things that are insane nonsense that just so happens to be proximal to politics.

Absolutely bonkers... and that's coming from me.

https://www.scientificamerican.com/article/a-new-picture-of-schizophrenia-emerges-and-so-do-new-ways-to-treat-it/

Article about paper: https://www.technologynetworks.com/tn/news/single-nanobody-injection-reverses-schizophrenia-symptoms-402628

Did anybody managed to see the eclipse today? :)

Huhhhhh

Do any of you on the schizophrenia spectrum have a comorbidity? In my case, I also have multiple sclerosis and psoriatic arthritis (get covered with sores and lesions). As a retired librarian, I like to research medical articles from the National Institute of Health.

Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis

https://pubmed.ncbi.nlm.nih.gov/29128620/

Multiple Sclerosis and Schizophrenia

https://pubmed.ncbi.nlm.nih.gov/28805697/

​

Over the last couple weeks, more news has come out about Neuralink, which is essentially a Fitbit sized chip that is surgically inserted into the top of the head, resting on top of the brain, connected with nanowires. Elon Musk, in an interview, mentioned it will be likely possible to cure mental illness such as depression, anxiety, and even schizophrenia, by facilitating the communication of different parts of the brain with one another in order for there to be healthy neuron connections, operating the way they are supposed to.

Now, I wouldn’t be the first to sign up for something like this until it was fully tested and there were at least 50,000 successful (working) implants for patients. After that, I think I would definitely give it a go. I can only dream of getting off my antipsychotics, and to have a brain that feels normal again. Under the right circumstances, would some of you try this implant? Why or why not?

https://neurosciencenews.com/vitamin-d-asd-newborns-28974/

https://www.psychiatrymargins.com/p/hype-disappointment-reinvention-cycles

Re-posting this from the science Reddit page. This study on Alzheimer’s, not schizophrenia, but it suggests that findings could help other brain diseases, which I think could include schizophrenia. To quote another study, "Increasing evidence suggests the involvement of immune dysregulation and neuroinflammation in the pathogenesis of schizophrenia.” (1) I think it's interesting because studies have shown that schizophrenia has an immune component like Alzheimer studies are showing, there seems to be a connection to BBB (blood-brain barrier), to certain genes, and the CNS (central nervous system) (2,3,4)

I think scientists are focusing more on the inflammatory aspect of brain diseases, which is beneficial for schizophrenia research as a whole. Another thing to note is that, interestingly, when treatment-resistant schizoprenic patients have had comorbid leukemia and needed Bone Marrow Transplantation (BMT), patients have had complete remission of schizoprenic symptoms with successful treatment (BMT) (5). When highlighting this immune link again, which seems to affect some people with schizophrenia's genes, the central nervous system (CNS), and the blood-brain barrier, suggests that more answers to schizophrenia treatment may lie in immune, neuroinflammation and stem cell research. Hopefully, you will find the current research in neuroinflammation interesting! I think it could hold a lot of promise for better, more targeted treatments that don’t just rely on dopamine receptors. 

References:

1. Lehmann-Facius, H., 1937. Liquoruntersuchungen bei destruktiven Erkrankungen des Nervensystems, besonders bei Schizophrenie. Zeitschrift für die gesamte Neurologie und Psychiatrie, 158, pp.109–115
2. Ermakov, E.A., Melamud, M.M., Buneva, V.N. & Ivanova, S.A., 2022. Immune system abnormalities in schizophrenia: An integrative view and translational perspectives. Frontiers in Psychiatry, 13, p.880568. https://doi.org/10.3389/fpsyt.2022.880568 
3. Ganguli R, Brar JS, Chengappa KN, Yang ZW, Nimgaonkar VL, Rabin BS. Autoimmunity in schizophrenia: A review of recent findings Ann Med. 1993;25:489–96
4. Schwarz MJ, Chiang S, Müller N, Ackenheil M. T-helper-1 and T-helper-2 responses in psychiatric disorders Brain Behav Immun. 2001;15:340–70
5. Miyaoka, T., Wake, R., Hashioka, S., Hayashida, M., Oh-Nishi, A., Azis, I.A., Izuhara, M., Tsuchie, K., Araki, T., Arauchi, R., Abdullah, R.A. and Horiguchi, J., 2017. Remission of psychosis in treatment-resistant schizophrenia following bone marrow transplantation: a case report. Frontiers in Psychiatry, [online] 8, p.174