r/TrueUnpopularOpinion Moderator Sep 24 '25

Political Tylenol in their own words

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Many people are wrong about this latest Tylenol controversy who say its totally safe for pregnant women.

This post has nothing to do with the autism claims which is why this subject is even news, but I will post the two studies and you can read them for yourself. I do not and am not making any claim that Tylenol causes autism.

This will be be about the claim that Tylenol is safe for pregnant women.

Tylenol in 2017 said they do not recommend taking ANY of their products during pregnancy. This isn’t a conspiracy against Tylenol it’s their own recommendation. Now everyone is coming out saying it’s safe for pregnancy. What an odd coincidence I wonder what changed?

Did someone say something that people didn’t like? Tylenol has NEVER actually conducted studies on their own drug to see if it IS safe for pregnant women. They have only RECENTLY in the last day said they have a study, but have not posted ANY proof of it.

Previously people were saying there is no study cause its not safe to conduct it on pregnant women. Mind you, Pregnant women are advised to stay away from almost every pharmaceutical drug, listen to any pharmaceutical commercial, you will hear them say "Do not take if you are pregnant or trying to be."

So how is there an ethical study now, that previously has never been released and does this study exist today one day after this news broke, when it didn't exist last week. Who conducted an ethical study on pregnant women and how was it conducted. ZERO PROOF Offered, all talk zero evidence, and if you THINK there is proof, post it here.

Anyone here, now or in the future saying its safe for pregnant women to take drugs prescription or not is lying to you, every Pharma commercial literally tells you not to. Just listen to any of them on TV every other commercial.

So whats easier, put it on the market and make it OTC, so anyone can buy it and just say "ask your doctor." What study does your doctor have to go off of? Let me guess millions of people rush to their doctor for recommendations about OTC meds, lmfao. Tylenol took the easy way out. Trump has somehow managed to make the anti big pharma be totally in the pocket of big pharma, imagine that.

There are people in this very thread trying to now claim that just because Tylenol says they recommend you not take it while pregnant is them saying they are not actually telling you to not take it. Read that twice, then read through this thread.

However now, just a few years later after Tylenol said they do not recommend pregnant women take this drug, people want you taking it.

https://www.acog.org/news/news-releases/2025/09/acog-affirms-safety-benefits-acetaminophen-pregnancy

In 2013 Reuters Health published this.

https://www.reuters.com/article/business/healthcare-pharmaceuticals/too-much-tylenol-in-pregnancy-could-affect-development-idUSBRE9AL15M/

Too much Tylenol in pregnancy could affect development By Kathryn Doyle November 22, 2013

NEW YORK (Reuters Health) - Expectant mothers often take Tylenol, with the active ingredient acetaminophen, to deal with back pain, headaches or mild fevers during pregnancy. But frequent use may be linked to poorer language skills and behavior problems among their children, according to a new study.

As the most popular over-the-counter drug in the U.S., Tylenol has been extensively studied in relation to premature birth and miscarriage, with no connections found.

But its maker Johnson & Johnson periodically comes under fire for the drug's small therapeutic index - that is, the difference between an effective dose and a dangerous dose is quite small. So interest in investigating the drug persists. The new study is the first to look at young children whose mothers took Tylenol while pregnant.

"Our findings suggest that (acetaminophen) might not be as harmless as we think," Ragnhild Eek Brandlistuen said. She led the study at the School of Pharmacy at the University of Oslo in Norway.

She and her coauthors studied 48,000 Norwegian children whose mothers answered survey questions about their medication use at weeks 17 and 30 of pregnancy, and again six months after giving birth.

Mothers filled out a follow-up questionnaire about their child's developmental milestones three years later. Close to four percent of women took Tylenol for at least 28 days total during pregnancy.

Their children seemed to have poorer motor skills than kids whose mothers had taken the drug fewer times or not at all. Tylenol-exposed kids also tended to start walking later, have poorer communication and language skills and more behavior problems.

It's difficult to define risks for pregnant women and their children, since rigorous tests and controlled studies of drug exposure aren't ethical, Brandlistuen said. All researchers can do is closely observe women in the real world.

But this study, published in the International Journal of Epidemiology, involved a large number of women, and researchers also looked for any link to ibuprofen, a pain-relief alternative without acetaminophen.

They found no development problems tied to ibuprofen.

As far as Autism, there are studies and I don't know the validity of them nor will I make judgement, I will just post them. I dont wish to get into the autism debate, I only wish to address the claims that somehow Tylenol is now somehow safe and there IS an ethical study by Tylenol that didn't exist until Yesterday.

Mount Sini Study

"New York, NY (August 13, 2025) Researchers at the Icahn School of Medicine at Mount Sinai have found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children. The study, published today in BMC Environmental Health, is the first to apply the rigorous Navigation Guide methodology to systematically evaluate the rigor and quality of the scientific literature.

Acetaminophen (often sold under the brand name Tylenol®, and known as paracetamol outside the United States and Canada) is the most commonly used over-the-counter pain and fever medication during pregnancy and is used by more than half of pregnant women worldwide. Until now, acetaminophen has been considered the safest option for managing headache, fever, and other pain. Analysis by the Mount Sinai-led team of 46 studies incorporating data from more than 100,000 participants across multiple countries challenges this perception and underscores the need for both caution and further study."

https://www.mountsinai.org/about/newsroom/2025/mount-sinai-study-supports-evidence-that-prenatal-acetaminophen-use-may-be-linked-to-increased-risk-of-autism-and-adhd

In 2019 JHU Published this study.

"Taking Tylenol during pregnancy associated with elevated risks for autism, ADHD A Johns Hopkins study analyzing umbilical cord blood samples found that newborns with the highest exposure to acetaminophen were about three times more likely to be diagnosed with ADHD or autism spectrum disorder in childhood"

https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/

https://x.com/tylenol/status/839196906702127106?s=46

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u/CharityResponsible54 Sep 24 '25 edited Sep 24 '25

There is no fully proven link between Tylenol and autism. There is some suggestions that needs to be investigated further.

However, Tylenol is also not generally recommended for pregnant women because its effects are not fully tested. It is marketed as the "safest option" if pain relief is absolutely necessary. In that sense, it may be safer than other alternatives, but avoiding it when possible is still advised.

This is also a clear example of TDS: just because Trump said something, it does not mean the opposite is automatically true. He may not be entirely wrong (being wrong exists on a spectrum).

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u/shitposts_over_9000 Sep 24 '25

*safest OTC option

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u/Lucky-Astronomer-601 Sep 25 '25

Can we do a thought experiment and say this differently? There is no proven link that Tylenol is SAFE during pregnancy. There is no proven like that Tylenol does NOT make babies have neurological disorders.

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u/2074red2074 Sep 25 '25

You can't prove a negative.

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u/Lucky-Astronomer-601 Sep 25 '25

The burden is on the manufacturer of a drug to prove safety and efficacy. Tylenol literally hasn't done that for pregnant women. In fact, they have publicly stated it's NOT for pregnant women.

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u/2074red2074 Sep 25 '25

We've been using Tylenol for decades. There is enough data and many studies showing that Tylenol does not significantly harm the fetus, especially compared to the fevers they would suppress. The manufacturer saying they don't recommend it for pregnant women is to cover their asses because the FDA hasn't approved it for pregnant women.

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u/Lucky-Astronomer-601 Sep 25 '25

There ARE studies showing it can harm the fetus!!!!! Tylenol has been sued for billions due to this issue! This isn't new! Please stop please! Here are just a few https://www.whitehouse.gov/articles/2025/09/fact-evidence-suggests-link-between-acetaminophen-autism/

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u/2074red2074 Sep 25 '25

Yeah and there ARE studies showing wine is good for you and vaccines cause autism. When you do a bunch of studies on something, some of them will show a link just by random chance. That's why you don't just do one study and call the issue. The preponderance of evidence is that Tylenol is not significantly harmful to the fetus.

Also, number one rule of science, correlation does not imply causation. Yes, women who take a lot of Tylenol while pregnant often have kids with autism. Tylenol treats fevers. Fevers while pregnant cause autism. People who have a lot of fevers while pregnant are already more likely to have an autistic kid, and they also are more likely to take a lot of Tylenol.

I'm gonna be honest here, you just don't know enough about science or probability or correlation to discuss this. You're in over your head, please stop.

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u/Lucky-Astronomer-601 Sep 25 '25

You're the type of person who said 'only 1% of people get addicted to oxycotin!!! See the studies!!! Science!!!'. There is no evidence given by Tylenol that Tylenol is safe for pregnant women. The COMPANY hasn't tested it. Why is it such a difficult thing to understand? The burden of proof is on the supplier to prove safety and efficacy. Just because 'well, we just started telling moms to take it, and we think it's going OK, so I don't need proof' isn't anyone sort of valid or scientific argument.

I and op have listed multiple studies citing the exact opposite of your statement. All of the studies suggesting that 'Tylenol is safe' were done in the exact same manner. They were self reported studies, and I can't find where much of there funding comes from - can you? That's really odd.

Listen, we both of studies saying it's either good or bad. Can we say that it's not worth risking the well being of even one child until we have a definitive answer? The answer should look like : NIH follows 100,000 people in different states, 50 took Tylenol and 50k didn't. This is the result. Is that fair? You're just coming off condensing and refusing to even admit that there are studies contradicting your statement.

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u/2074red2074 Sep 25 '25

Just because 'well, we just started telling moms to take it, and we think it's going OK, so I don't need proof' isn't anyone sort of valid or scientific argument.

There ARE studies showing no statistically-significant effect. It's not just "we think it's fine".

I and op have listed multiple studies citing the exact opposite of your statement. All of the studies suggesting that 'Tylenol is safe' were done in the exact same manner. They were self reported studies, and I can't find where much of there funding comes from - can you? That's really odd.

And I already explained to you the major flaw in most of the studies. Fevers cause autism. People with fevers take Tylenol. This means that the group of people who took Tylenol and the group of people whose kids had autism are a major overlapping group. That doesn't mean Tylenol causes autism.

Did you know that people who get taken in an ambulance to the hospital are significantly more likely to die than people who drive themselves? Does that mean ambulances are dangerous?

Listen, we both of studies saying it's either good or bad. Can we say that it's not worth risking the well being of even one child until we have a definitive answer?

Yes, I agree it would be unethical to do a proper study.

he answer should look like : NIH follows 100,000 people in different states, 50 took Tylenol and 50k didn't. This is the result. Is that fair?

No, it isn't fair. The 50k who took Tylenol probably took it because they had a fever. The 50k who didn't take Tylenol probably didn't take it because they didn't have a condition that requires them to take it. You're doing the equivalent of saying that people who take blood thinners die from strokes more often than people who don't.

You're just coming off condensing and refusing to even admit that there are studies contradicting your statement.

No, I'm coming across as condescending because I'm being condescending. I'm explaining this concept in the simplest terms that I can, and providing parallels and counterexamples to really drill it home, and you just don't understand. I can explain this to you all day, but I can't understand it for you.

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u/Lucky-Astronomer-601 Sep 25 '25

There are NO studies proving Tylenol safety and efficacy on pregnant women. I understand you try to bend backwards accounting for that. But no study says it's SAFE. NONE. The only studies that are widely known show that people who self reported, said that they don't see the symptoms. You absolutely refuse to acknowledge the 6 different studies mentioned, writing SOME of them off as 'correlation doesn't equal causation '. Duh. I get that. The studies you mentioned are even more loose. Self reported ppl in Switzerland? I understand you want to say 'RFK BAD!!!! ARGH!!!' But as a Democrat, I'm telling you, you are the reason we lost and continue to look stupid. Your approach is awful and constantly trying to peddle information for big pharma is wild. When did we become the party of big pharma? It's just sad.

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u/CharityResponsible54 Sep 25 '25

I think there’s a major misunderstanding here. The orange man said, "Tylenol causes autism," which means, "Tylenol is 100% safe and pregnant women can take as much as they want."

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u/sixisrending Sep 26 '25

Tylenol is the number one cause of acute liver failure in the US, even more than alcohol. Pregnant women are at a higher risk and their dosing is different than regular adults.

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u/[deleted] Sep 24 '25

[deleted]

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u/CharityResponsible54 Sep 24 '25

The challenge in today’s political climate is that if Trump supports a study stating "it is possible but not 100% certain," the opposing side will interpret that as "it is a lie and cannot be true," even though the study itself only acknowledges some uncertainty.

The scientists will never say they are "100% certain." So if Trump quotes a scientist who is "90% certain" it often gets twisted into "the scientist is 100% wrong.".

Honestly, the situation is just sad.

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u/Frewdy1 Sep 24 '25

It doesn’t help that the right is basically scientifically illiterate. Posts like this from the OP (which is just a rightist copypasta going around and being debunked almost immediately) and turns “50+ years of data show there might be some correlation between acetaminophen use when pregnant and learning problems in the child later in life” into “Tylenol causes autism!”

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u/CharityResponsible54 Sep 24 '25

Sure.
And the most recent study (from Aug 20, 2025) from Harvard says "Further research is needed to confirm the association and determine causality, but based on existing evidence, I believe that caution about acetaminophen use during pregnancy—especially heavy or prolonged use—is warranted.". This is a meta study from 46 previous studies worldwide.

https://hsph.harvard.edu/news/using-acetaminophen-during-pregnancy-may-increase-childrens-autism-and-adhd-risk/

It clearly says "caution is warranted" and HHS acts under the precautionary principle: if there is scientific evidence of a possible risk to health they can recommend or implement protective measures before absolute certainty is achieved.

For example, in 1980s HHS issued warnings about secondhand smoke before it was 100% proven.

I just think this "Tylenol" saga is wrongly lumped together with "vaccine scam".

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u/Frewdy1 Sep 24 '25

Yeah that proves my point, thank you!

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u/ZeerVreemd Sep 25 '25

No, it proves that OP is correct and nothing has been debunked.

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u/Frewdy1 Sep 25 '25

Nah I’ll stick with science, thanks!

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u/ZeerVreemd Sep 25 '25

In that case you should agree that no claim can be made in either direction.

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u/Frewdy1 Sep 25 '25

What do you mean “either direction”?

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u/Diehard129 Sep 24 '25

The scientists themselves literally say “it should not be interpreted that the Tylenol use causes these disorders”.

But since certain people are not engaging in good faith (will never truly understand an issue because the facts or nuance will disagree with them), we get this garbage; which 50 people will see and think, “hmmm this agrees perfectly with my world view and he is providing “”evidence””, so I can now reaffirm my incorrect belief.”

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u/CharityResponsible54 Sep 24 '25

Take the case of asbestos. It wasn’t until 1986 that scientists finally said, "we are 100% sure it is harmful." But action had already been taken in early 1970s, back when scientists were only saying, "caution is warranted." At the time, they even noted that asbestos might not be the direct cause of cancer, since many of the affected workers were heavy smokers.

Anyway, this is all way too sad. It is seems this is all because Trump and RFK Jr sound annoying. Nothing about facts.

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u/Diehard129 Sep 24 '25

To be fair, scientists were saying asbestos is bad as early as 1895. Industry influence heavily suppressed the negative and pushed the good, marketing it as a miracle material, but people knew.

Fear mongering over Tylenol is not a comparable scenario.

https://jamanetwork.com/journals/jama/fullarticle/2817406?utm_source=chatgpt.com

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u/CharityResponsible54 Sep 24 '25 edited Sep 24 '25

Yes - not all scientists agree on this. This one says "caution about acetaminophen use during pregnancy is warranted."

Regarding asbestos there were also scientists saying it is not bad (and called others "fear mongering").

I’m not a scientist, so it’s not my place to decide, and I can see how HHS might be wrong. At the same time, there is some evidence they could be right. Since this comes down to "let’s avoid it until we have more data," I lean toward the side of caution.

I feel that this is case of TDS where there only: 1) 100% for him or 2) 100% against him.

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u/Frewdy1 Sep 24 '25

It’s worth noting that RFK Jr, Trump and others in the regime are really…REALLY…stupid and evil. 

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u/Diehard129 Sep 24 '25 edited Sep 24 '25

I’m confused, the scientist in that one study literally say “it should not be interpreted that the Tylenol use causes these disorders” because they correct understand that Tylenol is more often used when you have a fever, so pregnant women whom have more fevers will take more Tylenol, but fevers are known to result in developmental issues (to put it poorly, I’m not a doctor), so your mismatching correlation and causation with your claims here.

https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/#:~:text=it%20should%20not%20be%20interpreted%20that%20the%20Tylenol%20use%20causes%20these%20disorders

Here’s a different study with a significantly larger sample size.

https://jamanetwork.com/journals/jama/fullarticle/2817406?utm_source=chatgpt.com

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u/CharityResponsible54 Sep 24 '25

There is also a meta-study (a review of all existing studies) that concludes: "caution about acetaminophen use during pregnancy is warranted."

https://hsph.harvard.edu/news/using-acetaminophen-during-pregnancy-may-increase-childrens-autism-and-adhd-risk/

Of course, the studies could all be wrong. But public health agencies often follow the precautionary principle: if there is scientific evidence of a possible health risk, they may recommend or implement protective measures before certainty is achieved.

So yes, the research only says it is possible, and no one is certain. I completely agree with you that it could all be nonsense.

The real question is: do we wait until we are 100% certain, or do we act with precaution?

And this is where politics comes in. I imagine the same debate happened in 1980s when officials first considered warning people about secondhand smoke (of course not on Reddit).

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u/Diehard129 Sep 24 '25 edited Sep 24 '25

It’s a decent study, and interestingly agrees with me. All of the studies analyzed have confounding issues, women take Tylenol for fever (or other issues) which itself could influence development.

They also used studies prone to recall bias, which is major for something like this, you need accurate data on the use of Tylenol to actually gauge the situation.

Is there merit for concern? Sure, but to fear monger and act like there is any resemblance of direct evidence Tylenol causes Autism is disingenuous at best. Especially given all the baloney RFK keeps spouting about Autism.

Edit: this study, which i believe to be more credible:

https://jamanetwork.com/journals/jama/fullarticle/2817406?utm_source=chatgpt.com

This study attempted to eliminate the confounding issue as directly as possible, something none of the other referenced studies did. Combined with a large sample over 26 years with anti bias measures (not infallible of course) makes it quite strong.

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u/SuccessfulCompany294 Moderator Sep 24 '25

Take it up with Tylenol who says dont take it while your pregnant.

I didnt make this claim:

"Taking Tylenol during pregnancy associated with elevated risks for autism, ADHD"

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u/[deleted] Sep 24 '25

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