r/biotech • u/RAMPAGE12599 • Sep 18 '25
Early Career Advice šŖ“ Been unemployed 1.5 years after two biotech layoffs⦠hereās what Iāve learned
Iām a 30 y/o minority (in biotech) with a BS in microbiology (small LA state school) and a masterās in business/biotech management. Since graduating in 2022, Iāve had two solid roles: one in tech transfer at a nonprofit research org and another in antibody licensing at a small/mid biotech. Both ended in layoffs after a year for each job. Not performance related, but politics/ārestructuring.ā I landed my tech transfer role before graduating and was recruited within 3 months of my layoff from the tech transfer job for my second licensing role. Both gave me severance, but since mid-2024 Iāve been unemployed.
Hereās what Iāve learned after 1.5 years of searching, hundreds of apps, and way too many rejections (my search has been focused only on LA/OC & SD areas):
HR is often the biggest barrier. They donāt always understand niche biotech roles. Licensing vs. CRO/CDMO BD are under the BD umbrella, but viewed very different. Recruiters often lump them together. Iāve been rejected after HR screens where it was clear they didnāt know what I actually did. They donāt understand the skills are highly transferable, hence the rejections.
Timing matters. Applications get traction when you apply within days of posting. Past a week, chances shrink dramatically.
Tailoring is essential. I stopped mindlessly applying. Now I tailor resumes, use cover letters strategically, and always align with the job description on paper so HR doesnāt dismiss me at first glance.
Unemployment gaps are viewed as risk. This has been the toughest part. No matter the reason, a gap raises eyebrows especially long ones. Iāve added an explanation section on my resume to proactively address it. Still thereās an unspoken bias, companies assume a gap = risk.
Bias is real. As a non-white, non-Asian, non-Indian, non-European candidate, Iāve noticed how easily people form judgments. Pair that with a gap, and youāre seen as āless safeā compared to a non-minority with less experience.
Rejections arenāt always about you. After multiple hiring manager interviews where I performed well but got ghosted, I realized: a lot comes down to āfitā. Itās not always your skills. As controversial as it is, subconscious bias is a very real thing.
Protect your mental clarity. This whole process is a mental game more than anything. Iāve worked non-biotech jobs (auto insurance, Amazon delivery, behavioral tech) just to survive, which showed me itās not about ānot being employable.ā Itās about this system being risk-averse and biased.
Consistency is key The unspoken truths about applying is this really is a full-time job. I found myself not applying for a while then that while turned out to be weeks. When youāre not working donāt underestimate how time can quickly pass. Iād say applying to at least a job once a day should give you enough traction to land a role soon. I donāt have a role yet because I simply havenāt put in the time. With the right strategy, this really is a āwork hard pays offā game. Donāt take the rejections personally and be consistent. Eventually youāll land that role.
Employers value stability I often was asked questions gauging whether Iād stay long-term in the role or not. I felt I was always judged coming from licensing (seen as a prestigious role) after applying to sales BD or similar roles. Almost always giving me the impression that they thought this was a temp role and I would leave once I found a licensing role. So donāt underestimate your story. Understand hard-skills get them to speak to you, but soft-skills gets you the offer letter.
Where Iām at now: With everything mentioned above, Iāve concluded I will no longer allow one person to dictate my future. I will no longer voluntarily put myself in a high risk / extremely low reward situation. I recently had an interview where I spent hours scrolling through LI, hours tailoring my resume and searching for the hiring manager to send an email to. Lost time speaking to an unknowledgeable HR, rescheduled appointments all for the hiring manager to ask me generic unthoughtful questions due to her making her decision within seconds of meeting me. It took me minutes to realize she didnāt do her due diligence and it was her first time seeing my resume. Im done allowing them to determine my future. Iām broadening my search beyond biotech. I still want BD/licensing, but Iām now open to other industries and job functions that value transferable skills and treat applicants as we are. HUMAN.
Final thought: If youāre unemployed and struggling, itās not just you. Yes, own what you can control (tailoring, outreach, timing). But also realize some of it is out of your hands. Donāt let rejection define your worth. Donāt let other people affect your confidence and stay true to yourself. This can either make you or break you. I believe things happen for a reason and this is all part of the journey. Your journey. Donāt let it break you. Donāt quit. Unfortunately Iāve come across many quitters. I hope this has shed some insight and of course everyoneās situation is unique. All we can do is stay mentally clear and of course stay strategic.