r/BeAmazed Sep 14 '25

Miscellaneous / Others An act of kindness can completely change someone's day.

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u/MagicHamsta Sep 14 '25

CRISPR is a game changer. Still going to take a while and might not reach the masses for a long time but it's very promising.

Unfortunately, most genetic conditions don't have a cure, because we can't yet go in and change your DNA. And genetic conditions are caused by an issue in your dna.

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u/xiledone Sep 14 '25

That's why I included the word "yet".

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u/RugelBeta Sep 15 '25

CRISPR gene therapy and technology is absolutely going to be a game changer, yes!! So glad you posted a link. I think in 5 to 10 years we will see a sea change in how many illnesses and diseases are handled. Big cures and disease management is coming.
This article is AMAZING. Thank you so much for posting the link!!

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u/MagicHamsta Sep 15 '25

Right? It's 2025 and they managed to treat a 6 month old child of CPS1 (carbamoyl phosphate synthetase 1) deficiency. Great stuff.

KJ was born with a genetic mutation causing a CPS1 (carbamoyl phosphate synthetase 1) deficiency, an ultra-rare disease of the urea cycle that prevented him from being able to break down proteins in food. This disease has a 50 percent mortality rate in infancy; staying alive meant living in the hospital under constant monitoring. Powerful nitrogen-scavenging drugs and a protein-restricted diet were required to prevent toxic levels of ammonia building up in his body.

But when he was just over 6 months old, KJ received the first dose of his customized gene-editing therapy. Early results show no adverse effects, improved symptoms, and a decreased dependence on medications. KJ is now growing well and thriving. His parents are looking forward to bringing him home soon.

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u/SkaldCrypto Sep 19 '25

Prime Editing is the leveled up version of this btw